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Comparison of tight junction protein mRNA expression levels in the control and functional dyspepsia (FD) groups in Helicobacter pylori-uninfected subjects. (A-C) Only claudin-2 (CLDN2) mRNA expression was significantly higher in male FD group than that of control group (P = 0.006). (D-F) There were no significant differences in CLDN2, CLDN4, and occludin (OCLN) mRNA expression level between female FD group and female control group. Data are expressed as median (interquartile range).
