Table 3.
The Mean Difference in the Quality of Life Scale (Short Form Nepean Dyspepsia Index) Between Groups
| Parameter | Clidinium/chlordiazepoxide (n = 37) | Placebo (n = 36) | P-value | ||||
|---|---|---|---|---|---|---|---|
| Baseline (mean ± SD) | Week 4 (mean ± SD) | Mean difference (95% CI) | Baseline (mean ± SD) | Week 4 (mean ± SD) | Mean difference (95% CI) | ||
| Overall | 30.38 ± 6.15 | 16.03 ± 4.86 | –14.35 (–16.48, –12.23) | 27.75 ± 7.24 | 24.31 ± 8.59 | –3.44 (–5.77, –1.11) | < 0.001 |
| Tension | 7.38 ± 1.69 | 3.76 ± 1.16 | –3.62 (–4.30, –2.94) | 6.58 ± 1.30 | 5.50 ± 1.80 | –1.08 (–1.71, –0.46) | < 0.001 |
| Interference with daily activities | 4.89 ± 2.71 | 2.73 ± 1.37 | –2.16 (–2.99, –1.34) | 4.44 ± 2.80 | 4.14 ± 2.44 | –0.31 (–0.92, 0.30) | 0.001 |
| Eating/drinking | 4.76 ± 1.86 | 3.14 ± 1.18 | –1.62 (–2.23, –1.02) | 5.08 ± 2.10 | 4.83 ± 1.96 | –0.25 (–0.91, 0.41) | 0.003 |
| Knowledge/control | 7.89 ± 1.54 | 3.62 ± 1.25 | –4.27 (–4.92, –3.62) | 7.31 ± 1.85 | 5.64 ± 2.03 | –1.67 (–2.38, –0.95) | < 0.001 |
| Work/study | 5.46 ± 2.86 | 2.78 ± 1.27 | –2.68 (–3.58, –1.77) | 4.33 ± 2.61 | 4.19 ± 2.55 | –0.14 (–0.76, 0.48) | < 0.001 |