Table 2.

Multilevel negative binomial regression results

	Adjusted results*
	IRR (95% CI)	P value
CLABSI rate
Preintervention slope	0.95 (0.77 to 1.19)	0.67
Shift in rates preintervention to intervention	0.90 (0.72 to 1.11)	0.32
Intervention slope	0.71 (0.53 to 0.96)	0.03
Intervention slope change	0.75 (0.52 to 1.08)	0.13
Central line utilisation rate
Preintervention slope	0.97 (0.94 to 0.99)	0.004
Shift in rates preintervention to intervention	1.01 (0.99 to 1.03)	0.51
Intervention slope	0.94 (0.91 to 0.96)	<0.001
Intervention slope change	0.97 (0.93 to 1.00)	0.09
CAUTI rate
Preintervention slope	0.96 (0.80 to 1.15)	0.66
Shift in rates preintervention to intervention	0.94 (0.79 to 1.12)	0.48
Intervention slope	0.76 (0.60 to 0.96)	0.02
Intervention slope change	0.79 (0.59 to 1.06)	0.12
Urinary catheter utilisation rate
Preintervention slope	0.95 (0.93 to 0.97)	<0.001
Shift in rates preintervention to intervention	1.00 (0.99 to 1.02)	0.73
Intervention slope	0.93 (0.91 to 0.95)	<0.001
Intervention slope change	0.98 (0.95 to 1.01)	0.14

*All models were adjusted for teaching status, urban or rural hospital location, type of hospital ownership, ICU bed size, ICU type, and whether or not the ICU focused its programme implementation efforts on the relevant infection (CLABSI, CAUTI or both).

CAUTI, catheter-associated urinary tract infection; CLABSI, central line-associated bloodstream infection; ICU, intensive care unit; IRR, incidence rate ratio.