Table 5.
The correlation between miR-548aq-3p and miR-550a-5p expression and clinical factors.
| Characteristic | Non smoking | miR-548aq-3p | miR-550a-5p | ||||
|---|---|---|---|---|---|---|---|
| −/↑ | ↓ | p-value | −/↑ | ↓ | p-value | ||
| Age, years | 1.000 | 1.000 | |||||
| <65 | 12 | 8 | 4 | 12 | 0 | ||
| >65 | 18 | 13 | 5 | 17 | 1 | ||
| Gender | 0.102 | 1.000 | |||||
| male | 18 | 15 | 3 | 17 | 1 | ||
| female | 12 | 6 | 6 | 12 | 0 | ||
| Involved diseased coronary arteries | 0.766 | 0.673 | |||||
| 1-Vessel | 4 | 3 | 1 | 4 | 0 | ||
| 2-Vessel | 9 | 7 | 2 | 9 | 0 | ||
| 3-Vessel | 17 | 11 | 6 | 16 | 1 | ||
| Coronary artery disease history | 1.000 | 0.467 | |||||
| − | 16 | 11 | 5 | 16 | 0 | ||
| + | 14 | 10 | 4 | 13 | 1 | ||
| Dyslipidemia | 0.687 | 0.367 | |||||
| − | 11 | 7 | 4 | 10 | 1 | ||
| + | 19 | 14 | 5 | 19 | 0 | ||
| Acute coronary syndrome | − | − | |||||
| − | 30 | 21 | 9 | 29 | 1 | ||
| + | 0 | 0 | 0 | 0 | 0 | ||
| Stroke / Transient ischemic attack | 0.083 | 0.067 | |||||
| − | 28 | 21 | 7 | 28 | 0 | ||
| + | 2 | 0 | 2 | 1 | 1 | ||
| Family history | 1.000 | 1.000 | |||||
| − | 27 | 19 | 8 | 26 | 1 | ||
| + | 3 | 2 | 1 | 3 | 0 | ||
| Hypertension | 1.000 | 1.000 | |||||
| − | 4 | 3 | 1 | 4 | 0 | ||
| + | 26 | 18 | 8 | 25 | 1 | ||
| Diabetes mellitus (DM) | 0.236 | 1.000 | |||||
| − | 16 | 13 | 3 | 15 | 1 | ||
| + | 14 | 8 | 6 | 14 | 0 | ||
| Smoking | − | − | |||||
| − | 30 | 21 | 9 | 29 | 1 | ||
| + | 0 | 0 | 0 | 0 | 0 | ||
| Chronic kidney disease (CKD) | 0.005 | 0.133 | |||||
| − | 26 | 21 | 5 | 26 | 0 | ||
| + | 4 | 0 | 4 | 3 | 1 | ||
Fisher’ Exact test.
Bold: p-value < 0.05.
−/↑The miRNA was not down-regulated after FIR treatment.
↓The miRNA was down-regulated after FIR treatment.