Table 4.
Unadjusted and adjusted analysis examining the correlations between high density lipoprotein cholesterol levels and the primary and secondary outcomes in non-ST elevation myocardial infarction patients who underwent percutaneous coronary intervention.
| All NSTEMI patients | All NSTEMI patients discharged alive | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Death during hospitalization | Death within 30 days from MI onset | Death within 1 year from MI onset | Rehospitalization for HF within 1 year from MI discharge | Rehospitalization for MI within 1 year from MI discharge | ||||||
| HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | HR (95% CI) | p | |
| Unadjusted | ||||||||||
| HDL-C in mmol/l | 0.78 (0.42–1.44) | 0.426 | 0.90 (0.50–1.62) | 0.728 | 1.26 (1.00–1.58) | 0.046 | 1.14 (0.93–1.39) | 0.218 | 1.23 (0.83–1.81) | 0.304 |
| Ordinal categories | ||||||||||
| >=1.6 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | |||||
| 1.0–1.5 | 1.75 (0.63–4.85) | 0.284 | 1.16 (0.46–2.89) | 0.752 | 0.78 (0.50–1.23) | 0.290 | 0.98 (0.53–1.82) | 0.952 | 1.10 (0.58–2.11) | 0.766 |
| <1.0 | 1.53 (0.55–4.27) | 0.415 | 1.08 (0.43–2.71) | 0.868 | 0.79 (0.50–1.25) | 0.313 | 0.75 (0.40–1.40) | 0.371 | 0.97 (0.51–1.86) | 0.935 |
| Adjusted* | ||||||||||
| HDL-C in mmol/l | 0.61 (0.26–1.39) | 0.236 | 0.68 (0.33–1.37) | 0.276 | 0.94 (0.69–1.28) | 0.700 | 1.06 (0.81–1.38) | 0.672 | 1.33 (1.12–1.58) | 0.001 |
| Ordinal categories | ||||||||||
| >=1.6 | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | 1.00 (ref) | |||||
| 1.0–1.5 | 6.57 (0.88–48.84) | 0.066 | 3.51 (0.84–14.68) | 0.086 | 1.54 (0.84–2.83) | 0.159 | 1.41 (0.62–3.21) | 0.411 | 1.08 (0.48–2.47) | 0.846 |
| <1.0 | 5.42 (0.73–40.54) | 0.099 | 3.27 (0.77–13.84) | 0.107 | 1.64 (0.89–3.03) | 0.112 | 1.15 (0.50–2.63) | 0.741 | 1.01 (0.44–2.35) | 0.978 |
*Adjusted for: oral medication for hyperlipidemia (yes/no/not applicable), age (numeric), sex (male/female), race (chinese/malay/indian/others), history of diabetes (yes/no), history of hypertension (yes/no), smoking status (never/former/current), history of AMI/CABG/PTCA (yes/no), BMI (numeric), Killip class on admission (1/2/3/4), CPR in ambulance/ED (yes/no), random blood glucose within 72 h from onset (numeric), creatinine on admission (numeric), haemoglobin on admission (numeric), elevated first troponin within 72 h from MI onset (yes/no), left ventricular ejection fraction <50% during hospitalization (yes/no).