Table 1.
Characteristics of the subjects according to CPAP usage and medications.
| non-OSA n = 14 | CPAP(−) | CPAP(+) | |||
|---|---|---|---|---|---|
| OSA-med(−) n = 11 | OSA-med(+) n = 5 | OSA-med(−) n = 11 | OSA-med(+) n = 9 | ||
| Age, years | 30.0 ± 1.5a | 44.0 ± 3.5b | 56.6 ± 4.5c | 43.8 ± 3.1b | 55.3 ± 3.1c |
| BMI, kg/m2 | 29.1 ± 2.1a | 34.0 ± 3.2a | 33.6 ± 2.9a | 48.1 ± 2.0b | 45.1 ± 1.7b |
| Male sex, n (%) | 6 (43%) | 7 (64%) | 3 (60%) | 2 (18%) | 1 (11%) |
| Dyslipidemia, n (%) | 0 (0%) | 0 (%) | 3 (60%) | 0 (0%) | 5 (56%) |
| Hypertension, n (%) | 0 (0%) | 2 (12%) | 3 (60%) | 5 (45%) | 7 (78%) |
| γH2AX & p16 (+) nuclei, % | 10.3 ± 0.7 | 26.2 ± 3.4 | 12.2 ± 4.9 | 23.0 ± 2.5 | 15.6 ± 2.4 |
Data are presented as mean ± SEM and the count with percentage (%). OSA – obstructive sleep apnea, BMI – body mass index, CPAP – continuous positive airway pressure, med – refers to medication including renin-angiotensin inhibitors, statins and/or aspirin, (+/−) – present or absent. Levels not connected by the same letter are significantly different (P < 0.05).