Table 5.
Risk for dementia by diabetes treatment status.
| Overall dementia | Early onset dementia | Late onset dementia | Alzheimer’s disease | Vascular dementia | |
|---|---|---|---|---|---|
| Normoglycemia | 1 (referent) | 1 (referent) | 1 (referent) | 1 (referent) | 1 (referent) |
| IFG | 1.06 (1.05–1.07) | 1.04 (1.01–1.07) | 1.06 (1.05–1.07) | 1.06 (1.05–1.07) | 1.06 (1.03–1.09) |
| Incident diabetes | 1.20 (1.18–1.22) | 1.21 (1.12–1.30) | 1.22 (1.20–1.24) | 1.18 (1.15–1.20) | 1.27 (1.21–1.34) |
| Treatment maintenance | 1.59 (1.57–1.60) | 1.70 (1.62–1.78) | 1.54 (1.52–1.55) | 1.56 (1.54–1.58) | 1.65 (1.60–1.70) |
| Treatment failure | 1.71 (1.66–1.76) | 2.07 (1.83–2.34) | 1.68 (1.64–1.73) | 1.63 (1.58–1.68) | 1.86 (1.73–2.01) |
| P value | <0.0001 | <0.0001 | <0.0001 | <0.0001 | <0.0001 |
Data were expressed as hazard ratio (95% confidence interval).
Abbreviation: IFG, impaired fasting glucose.
Adjusted for age, sex, body mass index, smoking status, alcohol use, exercise, hypertension, diabetes, dyslipidemia, myocardial infarction, stroke, and socioeconomic status.