Table 1:

Yeast DUB-E3 interactions

DUB	E3	Regulatory function of complex	Reference
Otu1	Ufd2	Cdc48 simultaneously engages both Ufd2 and Otu1, coupling activities to fine tune substrate ubiquitylation.	[47, 74]
Rpn11	Mms22	Rpn11 was detected in a proteomics screen for Mms22 interactors. Regulatory significance unknown.	[75]
Ubp2	Rsp5	Ubp2 interacts with Rsp5 and is reported to antagonize its function and also protects Rsp5 adaptors from degradation.	[33, 34, 62, 76]
Ubp15	Ssm4	Interaction detected in a high throughput two-hybrid screen. Regulatory significance unknown.	[77]