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. 2020 Apr 20;5(2):49–58. doi: 10.1016/j.synbio.2020.04.002

Fig. 2.

Fig. 2

Schematic diagram of positive and negative regulations. (A) positive regulation strategy: overexpression of positive regulators to promote the yield of metabolites; (B) negative regulation strategy: inhibition of the negative regulator expression to release the production of metabolites; (C) Combinatorial regulation strategy: coordination of positive and negative regulators to increase the yield of metabolites.