Fig. 1.

(A) The preparation process of near-infrared responsive 5-Fu-ICG-MPEG-PCL@HA MN, (B) The schematic illustration of the skin cancer treatment by 5-Fu-ICG-MPEG-PCL@HA MN under 808 nm laser within 5 min (1. The 5-Fu-ICG-MPEG-PCL was poured into the PDMS microneedle master structure; 2. centrifuged, and removed excess 5-Fu-ICG-MPEG-PCL; 3. the HA solution was poured on the PDMS template and 4. centrifuged; 5. the filled mold was dried in an oven at 45 °C overnight; 6. the as-prepared 5-Fu-ICG-MPEG-PCL@HA MN was taken from the PDMS mold gently.)