Table 4.

Summary of multivariate cox regression analysis for the prognosis of patients with ESCC.

End point	Prognostic factor	Hazard ratio	95% CI	P
OS
	Age(<60 vs. ≥60)	0.931	0.673–1.288	0.667
	Sex(Male vs. Female)	0.825	0.587–1.160	0.268
	Primary tumor location(baseline, Upper)			0.001
	Middle	1.422	1.056–1.914	0.020
	Lower	1.927	1.342–2.768	0.000
	T category (baseline, T2)			0.006
	T3	1.316	0.903–1.919	0.153
	T4	1.990	1.283–3.086	0.002
	Size of LNs (baseline, N0)			0.002
	>0.5 to ≤1 cm	1.309	0.906–1.893	0.152
	>1 to ≤2 cm	1.838	1.236–2.733	0.003
	>2 cm	2.116	1.345–3.329	0.001
	Treatment (CRT vs. RT alone)	0.669	0.510–0.878	0.004
PFS
	Age (<60 vs. ≥60)	0.829	0.628–1.094	0.185
	Sex (Male vs. Female)	0.931	0.696–1.246	0.630
	Primary tumor location(baseline, upper)			0.001
	Middle	1.381	1.069–1.786	0.014
	Lower	1.804	1.301–2.500	0.000
	T category (baseline, T2)			0.044
	T3	1.276	0.965–1.711	0.061
	T4	1.528	1.040–2.246	0.031
	Size of LNs (baseline, N0)			0.019
	>0.5 to ≤1 cm	1.267	0.926–1.734	0.139
	>1 to ≤2 cm	1.581	1.126–2.219	0.008
	>2 cm	1.740	1.159–2.614	0.006
	Treatment (CRT vs. RT alone)	0.754	0.621–0.936	0.010

LNs, lymph nodes; CI, confidence interval; CRT, chemoradiotherapy; RT, radiotherapy.