Table 3.
Functional enrichment analysis for genes in turquoise module
| Category | Term | Count | % | P‐value | q‐value |
|---|---|---|---|---|---|
| GO biological processes | Nuclear division | 51 | 38.35 | 1.47E‐55 | 3.06E‐51 |
| Reactome gene sets | Cell cycle | 54 | 40.60 | 1.04E‐49 | 5.38E‐46 |
| GO biological processes | Mitotic cell cycle phase transition | 37 | 27.82 | 8.01E‐29 | 1.39E‐25 |
| GO biological processes | Meiotic cell cycle | 27 | 20.30 | 2.47E‐27 | 3.66E‐24 |
| GO biological processes | Microtubule cytoskeleton organization | 34 | 25.56 | 7.84E‐26 | 9.04E‐23 |
| Canonical pathways | PID AURORA B PATHWAY | 13 | 9.77 | 1.69E‐20 | 9.22E‐18 |
| KEGG pathway | Cell cycle | 15 | 11.28 | 2.77E‐16 | 1.25E‐13 |
| GO biological processes | Cytokinesis | 16 | 12.03 | 1.71E‐15 | 6.57E‐13 |
| GO biological processes | DNA conformation change | 18 | 13.53 | 2.84E‐13 | 8.69E‐11 |
| GO biological processes | Attachment of spindle microtubules to kinetochore | 8 | 6.02 | 6.43E‐12 | 1.71E‐09 |
| GO biological processes | Positive regulation of cell cycle process | 16 | 12.03 | 9.44E‐12 | 2.45E‐09 |
| GO biological processes | Protein localization to chromosome | 10 | 7.52 | 2.78E‐11 | 6.95E‐09 |
| Reactome gene sets | Kinesins | 9 | 6.77 | 3.52E‐11 | 8.71E‐09 |
| GO biological processes | DNA replication | 15 | 11.28 | 3.68E‐11 | 8.88E‐09 |
| Reactome gene sets | APC/C‐mediated degradation of cell cycle proteins | 10 | 7.52 | 4.51E‐11 | 1.04E‐08 |
| GO biological processes | sister chromatid cohesion | 9 | 6.77 | 6.51E‐11 | 1.44E‐08 |
| GO biological processes | dna repair | 19 | 14.29 | 2.15E‐10 | 4.43E‐08 |
| GO biological processes | DNA integrity checkpoint | 11 | 8.27 | 1.17E‐09 | 2.12E‐07 |
| GO biological processes | Meiotic chromosome separation | 6 | 4.51 | 4.04E‐09 | 7.06E‐07 |
| GO biological processes | Chromosome condensation | 7 | 5.26 | 6.85E‐09 | 1.18E‐06 |
Abbreviation: GO, gene ontology; KEGG, Kyoto Encyclopedia of Genes and Genomes.