Table 3.
Expression of inflammatory cytokines in transfected myocardial cells in different groups after transfection (pg/mL)
| Group | IL‐1β | IL‐6 | IL‐10 | TNF‐α |
|---|---|---|---|---|
| Blank group | 82.46 ± 8.42 | 126.78 ± 13.04 | 67.84 ± 7.15 | 302.14 ± 17.2 |
| NC group | 82.78 ± 8.25 | 125.89 ± 12.77 | 68.02 ± 7.22 | 299.54 ± 17.42 |
| Mouse ATP2B1‐AS1 vector group | 130.25 ± 12.43* | 176.94 ± 16.12* | 32.14 ± 5.40* | 428.56 ± 16.88* |
| NFKBIA vector group | 50.12 ± 5.24*, & | 75.66 ± 8.03*, & | 124.76 ± 11.55*, & | 80.15 ± 8.32*, & |
| siRNA‐mouse ATP2B1‐AS1 group | 51.36 ± 6.77*, & | 80.42 ± 9.54*, & | 118.65 ± 10.12*, & | 94.67 ± 10.98*, & |
| siRNA‐NFKBIA group | 142.74 ± 5.22*, # | 183.65 ± 20.15*, # | 35.12 ± 4.65*, # | 415.88 ± 20.15*, # |
| Mouse ATP2B1‐AS1 vector + NFKBIA vector group | 88.96 ± 8.05 & , # | 120.72 ± 10.63 & , # | 70.22 ± 7.12 & , # | 286.32 ± 15.44 & , # |
| siRNA‐mouse ATP2B1‐AS1 + siRNA‐NFKBIA group | 85.42 ± 8.78 & , # | 132.95 ± 14.18 & , # | 68.37 ± 6.72 & , # | 314.75 ± 18.97 & , # |
Abbreviations: ATP2B1‐AS1, ATPase plasma membrane Ca2+ transporting 1; IL‐1β, interleukin 1β; IL‐6, interleukin‐6; NC, negative control; NFKBIA, NF‐kappa‐B inhibitor alpha; siRNA, small interfering RNA; TNF‐α, tumour necrosis factor α.
*
P < .05 vs the blank and NC groups.
&
P < .05 vs the mouse ATP2B1‐AS1 vector group.
#
P < .05 vs the siRNA‐mouse ATP2B1‐AS1 group.