Table 1.

List of proteins identified by LC‐MS/MS analysis in NPCE exosomes

Adhesion	CD44, CD59, CD9, integrin α, β, EDIL3
Antigen presentation	β‐2‐microglobulin, HLA class I histocompatibility antigen
Chaperons	Hsc70, Hsp71, Hsp90, T‐complex protein‐1 ε
Cytoskeleton	Actin α, β, α‐actinin, cofilin, collagen, ezrin, filamin, keratin, moesin, myosin‐6,9, prelamin, profilin, talin, tropomyosin α, tubulin α, β, vimentin, vinculin
Enzymes	ATPase NA+/K+ transporting, α‐enolase, D‐3‐phosphoglycerate dehydrogenase, G6PD, glyceraldehyde‐3‐phosphate dehydrogenase, fructose‐bisphosphate aldolase, L‐lactate dehydrogenase, malate dehydrogenase, nucleoside diphosphate kinase, phosphoglycerate mutase, phosphoglycerate kinase, pyruvate kinase, peptidylprolyl isomerase, protein disulphide‐isomerase, transitional endoplasmic reticulum ATPase, triosephosphate isomerase, ubiquitin carboxyl‐terminal hydrolase isozyme, valosin‐containing protein
Lectin binding	Galectin‐1
Vesicles trafficking & fusion	Annexins (1,2,5,6), clathrin heavy chain, Rab GDI, Rap 1B, WD RCP1
Others	Basigin, BASP1, calmodulin, importin, histones (H1.2, H1.5, H2A, H2B, H4), transgelin, protein DJ‐1, S100 protein
Oxidative stress response	Glutathione S‐transferase, peroxiredoxin‐1, superoxide dismutase
Protein synthesis	Initiation factor 4A, elongation factor (1,2), ribosomal proteins (40 S, 60 S subunit)
RNA/ DNA binding	Heterogeneous nuclear ribonucleoprotein, histidine triad nucleotide‐binding protein 1, nucleophosmin
Signal transduction	14‐3‐3 (ε, η, ζ), Rac (1,2,3), G proteins
Transporters	SLC3A2, chloride intracellular channel protein 4