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. 2020 Apr 16;8:232. doi: 10.3389/fcell.2020.00232

FIGURE 4.

FIGURE 4

ANXA6 contributes to autophagy incidence via inhibition of the PI3K/AKT/mTOR pathway. (A) Western blot assay of PI3K-α, AKT, p-AKT, mTOR, and p-mTOR proteins in HNE2, CNE1, and CNE1R cells. (B) Western blot assay of PI3K-α, AKT, p-AKT, mTOR, and p-mTOR proteins in CNE1R cells with or without siANXA6 transfection. (C) Western blot assay of PI3K-α, AKT, p-AKT, mTOR, p-mTOR, and ANXA6 proteins in siANXA6-transfected CNE1R cells treated with CAL101 or its control (1‰ DMSO). *P < 0.05 between indicated groups.