Skip to main content
. 2020 Apr 16;16:756–762. doi: 10.3762/bjoc.16.69

Table 2.

Optimization of reaction conditions.

entry product reagent base 11/12 ratioa yieldb
1 11a PyFluor MTBD 73:27 61%
2 11b PyFluor MTBD 60:40 47%
3 11c PyFluor MTBD 87:13 70%
4 11d PyFluor MTBD 68:32 59%
5 11e PyFluor MTBD 82:18 69%

aCrude reaction mixture ratio based on 31P NMR and 19F NMR; bYield of α-fluorides 11 after isolation.