Table 1.

Characteristics of the study population

Time point	Cognitive impairment	Disease progression	Eligible patients
1 (before treatment)	0	-	335
2 (3 mo)	20	12	303
3 (6 mo)	15	16	272
4 (9 mo)	56	24	192
5 (12 mo)	27	26	139
6 (15 mo)	10	17	112
7 (18 mo)	19	11	82
Total	147	106