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. 2019 Dec 31;52(2):622–633. doi: 10.4143/crt.2019.593

Fig. 2.

Fig. 2.

Chemokine (C-X-C motif) ligand 13 (CXCL-13) is elevated in 5-fluorouracil (5-Fu) resistant colorectal cancer patient and predicts clinical outcomes. (A) Comparison of the levels of CXCL-13 protein were measured by enzyme-linked immunosorbent assay in 5-Fu–sensitive (n=9) and –resistant (n=9) colorectal cancer patients, patients are shown in Table 1. Sen, sensitive cases; Res, resistant cases. (B) 6-Year overall survival (OS) Kaplan–Meier survival curves grouped by serum CXCL-13 expression levels (118 pg/mL) of 64 colorectal cancer patients, as patient information is shown in Table 2. (C) Six-year disease-free survival (DFS) Kaplan–Meier survival curves grouped by serum CXCL-13 expression levels (118 pg/mL) of 64 colorectal cancer patients, as patient information is shown in Table 2. (A) *p < 0.05, **p < 0.01 by unpaired Student’s t test. (B, C) *p < 0.05 by log-rank (Mantel-Cox), hazard ratios (HRs) and 95% confidence interval (CI) are shown.