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. 2020 Jan 6;52(2):634–644. doi: 10.4143/crt.2019.207

Table 1.

Thirty-nine genes associated with hereditary ovarian cancer

Pathway Gene
Hereditary breast and ovarian cancer syndrome BRCA1, BRCA2
Homologous recombination pathway ATM, ATR, BARD1, BRIP1, CHEK1, CHEK2, FAAP24, FAM175A (ABRAXAS1), FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, SLX4 (FANCP), MRE11A, NBN, PALB2, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RAD52, RAD54B, RAD54L
Mismatch repair MLH1, MSH2, MSH6, PMS2, EPCAM, MLH3
p53 TP53