Table 1.
Pathway | Gene |
---|---|
Hereditary breast and ovarian cancer syndrome | BRCA1, BRCA2 |
Homologous recombination pathway | ATM, ATR, BARD1, BRIP1, CHEK1, CHEK2, FAAP24, FAM175A (ABRAXAS1), FANCA, FANCB, FANCC, FANCD2, FANCE, FANCF, FANCG, FANCI, FANCL, FANCM, SLX4 (FANCP), MRE11A, NBN, PALB2, RAD50, RAD51, RAD51B, RAD51C, RAD51D, RAD52, RAD54B, RAD54L |
Mismatch repair | MLH1, MSH2, MSH6, PMS2, EPCAM, MLH3 |
p53 | TP53 |