TABLE 4.
Results of plasma and stool methylated SEPT9 tests in detecting CRC for different ages, genders, tumor locations and tumor sizes.
| Plasma | Stool | |||||
| Number (N) | PDR [%(n/N)] | p-value | Number (n/N) | PDR [%(n/N)] | p-value | |
| Age | ||||||
| <60 | 37 | 83.7% (31/37) | 0.690 | 35 | 80.0% (28/35) | 0.460 |
| ≥60 | 53 | 86.8% (46/53) | 37 | 86.5% (32/37) | ||
| Gender | ||||||
| Male | 53 | 90.6% (48/53) | 0.106 | 39 | 94.8% (37/39) | 0.020 |
| Female | 37 | 78.4% (29/37) | 33 | 69.7% (23/33) | ||
| Location | ||||||
| Distal | 39 | 87.2% (34/39) | 0.814 | 33 | 72.7% (24/33) | 0.056 |
| Proximal | 41 | 85.3% (35/41) | 33 | 90.9% (30/33) | ||
| N/A | 10 | 80.0% (8/10) | 6 | 100.0% (6/6) | ||
| Size | ||||||
| <3 cm | 12 | 75.0% (9/12) | 0.184a | 11 | 90.9% (10/11) | 0.549a |
| 3–6 cm | 48 | 89.6% (43/48) | 0.618b | 43 | 83.7% (36/43) | 0.382b |
| >6 cm | 13 | 84.6% (11/13) | 0.548c | 4 | 100.0% (4/4) | 0.533c |
| N/A | 17 | 82.4% (14/17) | 14 | 78.6% (11/14) | ||
N/A, not applicable. ap-value between <3 cm and 3–6 cm; bp-value between 3–6 cm, and >6 cm; cp-value between <3 cm and >6 cm.