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Experimental validation of the key signaling pathways in vivo. N-butanol extract of Taohe-Chengqi decoction (NE-THCQ) inhibited PI3K/ AKT/mTOR (A) and HIF-1α/VEGF (B) signaling pathways in the kidneys of unilateral ureteral obstruction (UUO) rats. Data were presented as mean standard deviation (SD) of three independent experiments. *P < 0.05, **P < 0.01.
