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. 2020 Apr 16;11:425. doi: 10.3389/fphar.2020.00425

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Copyright © 2020 Zhou, Ai, Li, You, Wu, Li, Hu and Ba

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The networks of n-butanol extract of Taohe-Chengqi decoction (NE-THCQ) on antirenal fibrosis. (A) The compound-target network of NE-THCQ. The orange nodes represent active compounds and the blue nodes represent targets. Nodes size and color depth are proportional to their degree. Edge widths are proportional to the edge betweenness. (B) The protein-protein interaction (PPI) network of protein targets obtained from STRING database and constructed by Cytoscape. The colors of the nodes are illustrated from dark orange to yellow to blue in descending order of degree values.