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. 2020 Apr 16;11:702. doi: 10.3389/fmicb.2020.00702

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Copyright © 2020 Lakkavaram, Lundie, Do, Ward and de Koning-Ward.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of pro-inflammatory and anti-inflammatory cytokines and chemokines during P. berghei infection. Levels of proinflammatory cytokines (A), anti-inflammatory cytokines (B), and chemokines (C) were measured with a ProcartaPlex Mouse Cytokine and Chemokine Panel 1 kit and those that were significantly upregulated in the serum of infected mice at 7 dpi are shown. The lower limits of detection are indicated by a dotted line. Data represents results from individual mice as well as the mean ± SD (n = 6 mice). An unpaired t-test was used to calculate statistical significance: *p < 0.05, **p < 0.01, ***p < 0.001.