TABLE 4.
Number of SNPs located within known age-related genes and in their promoter regions.
| old_rep1 | old_rep2 | Overlap | |
| Number of longevity-related genes in dogs1 | 1062 | ||
| Number of exonic SNP | 86621 | 86521 | 55159 |
| Number of novel exonic SNP | 1371 | 1461 | 327 |
| Number of novel, missense SNP mutations | 376 (257) | 361 (261) | 67 (37) |
| Number of age-related genes with missense mutation(s) | 9 (8) | 16 (12) | 1 (1) |
| Number of genes with novel SNP in regulatory regions2 | 7014 (4370) | 8181 (5005) | 1861 (887) |
| Number of age-related genes with mutations in regulatory regions2 | 411 (159) | 464 (168) | 200 (31) |
Number of affected genes are shown in parenthesis. 1The definition of longevity-related genes is provided in the materials and methods section; 2defined as 5 kb upstream and downstream of gene body.