TABLE 3.
Details of overlapping genes in Type I and II of shared risk genes.
| Genes1 | PmetaCCA |
Asthma |
Hay fever |
Eczema |
Literature PMID | |||
| PMAGMA | PMetaXcan | PMAGMA | PMetaXcan | PMAGMA | PMetaXcan | |||
| TNXB† | 7.12e-29 | 3.51e-35 | 1.39e-10 | 1.20e-09 | 23886662 | |||
| C6orf10‡ | 1.60e-18 | 1.59e-22 | 1.01e-12 | 9.84e-10 | 21804548, | |||
| 23042114 | ||||||||
| CLEC16A* | 8.26e-16 | 4.24e-22 | 3.51e-10 | 5.92e-11 | 31036433, | |||
| 30013184, | ||||||||
| 26482879 | ||||||||
| C2* | 1.84e-06 | 1.31e-14 | 3.51e-21 | 1.08e-13 | 5.06e-08 | 1.45e-08 | 29551627, | |
| 25085501, | ||||||||
| 26542096 | ||||||||
| WDR36* | 1.95e-26 | 1.61e-24 | 5.68e-14 | 2.58e-14 | 2.52e-08 | 30929738, | ||
| 24388013, | ||||||||
| 30595370 | ||||||||
| PSORS1C2 | 3.54e-15 | 3.77e-13 | 6.80e-07 | |||||
| HLA-DMB | 7.72e-14 | 6.67e-14 | 3.34e-07 | |||||
| BTNL2† | 1.14e-12 | 1.03e-59 | 5.08e-09 | 29273806 | ||||
| BAG6 | 5.69e-11 | 9.44e-19 | 6.64e-15 | 7.05e-10 | 6.03e-18 | |||
| SLC25A46* | 2.79e-09 | 1.35e-09 | 9.52e-09 | 31036433, | ||||
| 22036096, | ||||||||
| 30595370 | ||||||||
| CAMK4‡ | 2.31e-08 | 5.12e-11 | 1.28e-08 | 29785011, | ||||
| 30013184 | ||||||||
| MUC22 | 8.56e-07 | 1.56e-13 | 2.01e-11 | |||||
| PLCL1‡ | 6.08e-06 | 2.23e-06 | 9.73e-12 | 30013184, | ||||
| 30595370 | ||||||||
| RNF5 | 4.31e-17 | 1.75e-12 | 3.39e-13 | 2.06e-10 | 5.84e-11 | |||
| KIF3A‡ | 7.05e-16 | 5.35e-13 | 6.57e-14 | 7.51e-08 | 31036433, | |||
| 26542096 | ||||||||
| DDAH2 | 1.78e-07 | 1.43e-08 | 3.10e-08 | |||||
| RAD50* | 4.05e-06 | 6.20e-29 | 9.21e-31 | 6.36e-07 | 30929738, | |||
| 30013184, | ||||||||
| 26482879 | ||||||||
1Symbol, ‡, and * behind the genes represents 1, 2, and 3 associated diseases (asthma, hay fever, eczema) reported in GWAS-catalog, respectively. PMID, PubMed unique identifier. The blank cells are non-significant p-values or no supporting literature.