Table 2.
Effect of chronic quercetin treatment on left ventricular function in doxorubicin treated rats.
| Groups | Coronary flow rate (ml/min) | +(dp/dt) max (mmHg/s) | -(dp/dt) max (mmHg/s) |
|---|---|---|---|
| Control | 18.33 ± 0.81 | 3186.91 ± 194.16 | 2319.78 ± 184.14 |
| DOXO | 12.33 ± 0.58# | 1550.17 ± 125.17# | 1112.63 ± 112.82# |
| Quercetin (10 mg/kg) + DOXO | 14.87 ± 0.82∗ | 1988.13 ± 73.24∗ | 1611.27 ± 67.31∗ |
| Quercetin (25 mg/kg) + DOXO | 15.88 ± 0.83∗ | 2161.76 ± 99.38∗ | 1785.23 ± 54.95∗ |
| Quercetin (50 mg/kg) + DOXO | 15.71 ± 1.21∗ | 2077.57 ± 118.55∗ | 1654.31 ± 54.11∗ |
All values are presented as mean ± SD.
#P < 0.05 as compared to the control group.
∗P < 0.05 as compared to doxorubicin (DOXO) group.