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. 2020 Apr 16;14:354. doi: 10.3389/fnins.2020.00354

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Copyright © 2020 Wang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Methodological aspects to consider in the study of circulating miRNAs as biomarkers for ALS and other MNDs. The comparison among the common characteristics of miRNA detection platforms are summarized in the figure. qRT-PCR, quantitative Real-Time Polymerase Chain Reaction; NGS, Next Generation Sequencing.