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. 2020 Apr 23;158(1):406–415. doi: 10.1016/j.chest.2020.04.020

Table 2.

Current (Pre-COVID-19) Guidelines for the Evaluation of Subsolid Lung Nodules

CHEST4 The Fleischner Society5 Lung-RADS7 BTS6
< 6 mm
GG: No routine follow-up
< 6 mm
GG: No routine follow-up
PS: No routine follow-up
Multiple: CT scan at 3-6 mo, consider CT at 2 and 4 y if stable
GG: < 30 mm or any size and unchanged: RTAS (category 2)
PS: < 6 mm: baseline RTAS (category 2), new 6-mo CT (category 3)
< 5 mm: No follow-up
≥ 6 mm
GG: 12 mo then annual through 3 y
PS: ≤ 8 mm solid, 3, 12, and 24 mo, then annual mo, then annual until 5 y;
> 8 mm solid, 3 mo, further evaluation if persists
≥ 6 mm
GG: 6-12 mo then every 2 y until 5 y
PS: 3-6 mo then annual until 5 y
Multiple: 3-6 mo then based on most suspicious nodule
GG: > 30 mm or new: 6-mo CT scan (category 3)
PS: solid component < 6 mm, 6-mo CT (category 3); solid component ≥ 6-8 mm or new or growing and < 4 mm, 3-mo CT (category 4A); solid component ≥ 8 mm or new or growing and ≥ 4 mm, further evaluation (category 4B)
≥ 5 mm: 3-mo CT growth or altered morphology favors resection, stable, use Brock model, < 10% then CT scan at 1, 2, and 4 y from baseline, > 10% or concerning morphology, surveillance, biopsy, or resection

GG = ground-glass; PS = part-solid. See Table 1 legend for expansion of other abbreviations.