6.

Summary receiver operator curve plot of sensitivity versus specificity for performance of different tests versus coronary angiography: Indirect comparison MPS versus DSE. Each symbol represents a study, with the height and width of each symbol being proportional to the inverse standard error of the sensitivity and specificity respectively. The curves represent the summary receiver operator characteristic curves for MPS and DSE. The circles represent the summary estimate of test performance and the zone outline surrounding it represents the 95% confidence region of this summary estimate

DSE: dobutamine stress echocardiography; MPS: myocardial perfusion scintigraphy