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. 2011 Dec 7;2011(12):CD008691. doi: 10.1002/14651858.CD008691.pub2

Bennett 1978.

Clinical features and settings Clinical features
  • Patients with juvenile insulin‐dependent DM and ESKD who presented for kidney transplant cardiac evaluation. Eleven patients with evidence of arteriosclerotic heart disease gave their informed consent for coronary arteriogram and left ventricular angiogram. Seven patients had EST.


Setting
  • University of Oregon Health Sciences Center, Oregon, USA

Participants
  • Number: 4 participants

  • DM: 100%

  • Angina pectoris: percentage of patients with angina not reported

  • Hypertension:, 100%

  • Sex: 36% male

Study design Cohort study
Target condition and reference standard(s) Coronary artery stenosis measured by coronary angiography
  • Absolute degree of stenosis recorded for each patient.

Index and comparator tests EST
Follow‐up 30‐38 months, unless death occurred earlier.
Notes Three of the seven patients had a non‐diagnostic stress test due to inadequate rate as a result of fatigue.
Table of Methodological Quality
Item Authors' judgement Description
Representative spectrum? 
 All tests Yes Patients with juvenile insulin‐dependent DM and ESKD who presented for kidney transplant cardiac evaluation.
Acceptable reference standard? 
 All tests Yes Coronary artery stenosis measured by coronary angiography. Absolute degree of stenosis recorded for each patient.
Acceptable delay between tests? 
 All tests Unclear Unclear, but likely to be only short delay between tests.
Partial verification avoided? 
 All tests Yes All patients received angiography.
Differential verification avoided? 
 All tests Yes This was not an issue in this study. Disease status (CAD) is diagnosed only through coronary angiography.
Incorporation avoided? 
 All tests Yes This was not an issue in this study. Disease status (CAD) is diagnosed only through coronary angiography.
Reference standard results blinded? 
 All tests Unclear Not reported.
Index test results blinded? 
 All tests Unclear Not reported.
Relevant clinical information? 
 All tests Yes Relevant clinical information was provided regarding the performance and analysis of both the index and reference tests.
Uninterpretable results reported? 
 All tests Yes No results were reported to be uninterpretable.
Withdrawals explained? 
 All tests Yes All patients missing from the final analysis were accounted for.