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Diagram summarizing the main interactions of Müller cells (blue) with RGCs (orange). Scheme showing the roles of Müller cells in RGC neuroprotection, such as glucose metabolism regulation, water and ion homeostasis, neurotransmitters uptake, antioxidant defense systems (GSH) against ROS, secretion of trophic factors. The role of Müller cells in inflammation by secretion of cytokines that may be detrimental for RGCs is also depicted (red arrow).
