Table 1.
A comparison between MF-based PLGA NPs and the NPs produced by other conventional methods in terms of size, polydispersity index (PDI) and encapsulation efficiency (EE) values reported in the literature.
| Formulation/Method | NPs Size (nm) | EE (%) | PDI | Reference |
|---|---|---|---|---|
| 5-FU loaded poly (3-hydroxybutyrate-co-3-hydroxyvalerate) (PHBV)/PLGA NPs/emulsion | ~135 | ~43 | ≤1 | [40] |
| 5-FU Loaded PLGA and PCL NPs a simple/emulsion method [without poly (ethylene glycol) (PEG)] | ~24 | ~32 | 0.137 | [41] |
| 5-FU-PLGA NPs/nanoprecipitation | ~133 | ~40 | 0.352 | [42] |
| 5-FU loaded PLGA NPs/MF technique | ~101 | ~95 | 0.083 | Current study |