Comparison 1. Resin fissure sealant versus fluoride varnish.

Outcome or subgroup title	No. of studies	No. of participants	Statistical method	Effect size
1 Caries at 23 to 24 months (yes/no)	2		Odds Ratio (Fixed, 95% CI)	0.69 [0.50, 0.94]
1.1 Split‐mouth studies with paired data	1		Odds Ratio (Fixed, 95% CI)	0.67 [0.48, 0.93]
1.2 Parallel‐group studies	1		Odds Ratio (Fixed, 95% CI)	0.87 [0.34, 2.20]
2 Caries at 4 years (yes/no)	1		Risk Ratio (Fixed, 95% CI)	0.42 [0.21, 0.84]
3 Caries at 9 years (yes/no)	1		Risk Ratio (Fixed, 95% CI)	0.48 [0.29, 0.79]