Table 1.
Relationship between clinical parameters and mRNA expression of PDGF and PDGFR in OSCC patients.
| Variables | N | PDGFA | PDGFB | PDGFRA | PDGFRB | ||||
|---|---|---|---|---|---|---|---|---|---|
| Mean ± SEM | p-Value | Mean ± SEM | p-Value | Mean ± SE | p-Value | Mean ± SEM | p-Value | ||
| Gender | |||||||||
| Male | 117 | 9.63 ± 1.02 | 0.124 | 6.37 ± 0.77 | 0.502 | 3.25 ± 0.62 | 0.303 | 10.99 ± 1.29 | 0.615 |
| Female | 9 | 16.81 ± 10.59 | 8.29 ± 3.87 | 0.93 ± 0.34 | 13.47 ± 5.63 | ||||
| Age | |||||||||
| < 54 | 70 | 9.95 ± 1.30 | 0.858 | 7.46 ± 1.13 | 0.147 | 3.29 ± 0.91 | 0.696 | 11.55 ± 1.65 | 0.740 |
| ≥ 54 | 56 | 10.38 ± 2.17 | 5.32 ± 0.83 | 2.83 ± 0.64 | 10.70 ± 1.96 | ||||
| T stage | |||||||||
| T1-2 | 32 | 8.54 ± 2.12 | 0.440 | 5.70 ± 1.29 | 0.521 | 3.23 ± 1.06 | 0.884 | 9.93 ± 2.42 | 0.567 |
| T3-4 | 94 | 10.68 ± 1.44 | 6.78 ± 0.88 | 3.03 ± 0.69 | 11.59 ± 1.48 | ||||
| N status | |||||||||
| N0 | 80 | 7.34 ± 1.07 | 0.002 ** | 5.10 ± 0.90 | 0.011 * | 2.27 ± 0.42 | 0.064 | 9.05 ± 1.50 | 0.026 * |
| N+ | 46 | 15.00 ± 2.57 | 8.95 ± 1.17 | 4.49 ± 1.39 | 14.85 ± 2.17 | ||||
| Stage | |||||||||
| I-II | 21 | 6.41 ± 1.79 | 0.165 | 3.33 ± 0.81 | 0.051 | 1.39 ± 0.51 | 0.192 | 5.51 ± 2.45 | 0.045 * |
| III-IV | 105 | 10.89 ± 1.39 | 7.14 ± 0.85 | 3.42 ± 0.68 | 12.30 ± 1.41 | ||||
| Lymphovascular invasion | |||||||||
| No | 108 | 9.48 ± 1.28 | 0.185 | 6.33 ± 0.08 | 0.557 | 2.46 ± 0.43 | 0.445 | 10.31 ± 1.28 | 0.078 |
| Yes | 18 | 14.04 ± 3.37 | 7.57 ± 1.80 | 3.41 ± 1.62 | 16.32 ± 3.12 | ||||
| Perineural invasion | |||||||||
| No | 97 | 9.85 ± 1.46 | 0.664 | 6.01 ± 0.81 | 0.216 | 2.84 ± 0.48 | 0.438 | 10.22 ± 1.32 | 0.169 |
| Yes | 29 | 11.10 ± 1.85 | 8.16 ± 1.67 | 3.91 ± 1.95 | 14.35 ± 3.21 | ||||
*, p < 0.05; **, p < 0.01.