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. 2020 Mar 29;21(7):2360. doi: 10.3390/ijms21072360

Table 2.

Relationship between clinical parameters and immunoexpression of PDGF and PDGFR in OSCC patients.

Variables N PDGF PDGFRA PDGFRB
Low High p-Value Low High p-Value Low High p-Value
Gender
 Male 57 25 (43.9%) 32 (56.1%) 0.773 33 (57.9%) 24 (42.1%) 0.710 35 (61.4%) 22 (38.6%) 0.184
 Female 6 3 (50.0%) 3 (50.0%) 3 (50.0%) 3 (50.0%) 2 (33.3%) 4 (66.7%)
Age
 <54 35 17 (48.6%) 18 (51.4%) 0.461 21 (60.0%) 14 (40.0%) 0.608 23 (65.7%) 12 (34.3%) 0.208
  ≥54 28 11 (39.9%) 17 (60.7%) 15 (53.6%) 13 (46.4%) 14 (50.0%) 14 (50.0%)
T stage
  T1-2 14 8 (57.1%) 6 (42.9%) 0.278 10 (71.4%) 4 (28.6%) 0.221 9 (64.3%) 5 (35.7%) 0.632
 T3-4 49 20 (40.8%) 29 (59.2%) 26 (53.1%) 23 (46.9%) 28 (57.1%) 21 (42.9%)
N status
  N0 36 21 (58.3%) 15 (41.7%) 0.010 * 26 (72.2%) 10 (27.8%) 0.005 ** 26 (72.2%) 10 (27.8%) 0.012 *
  N+ 27 7 (25.9%) 20 (74.1%) 10 (37.0%) 17 (63.0%) 11 (40.7%) 16 (59.3%)
Stage
  I-II 7 4 (57.1%) 3 (42.9%) 0.473 5 (71.4%) 2 (28.6%) 0.418 5 (71.4%) 2 (28.6%) 0.469
 III-IV 56 24 (42.9%) 32 (57.1%) 31 (55.4%) 25 (44.6%) 32 (57.1%) 24 (42.9%)
Lymphovascular invasion
 No 51 24 (47.1%) 27 (52.9%) 0.389 31 (60.8%) 20 (39.2%) 0.229 33 (64.7%) 18 (35.3%) 0.047 *
 Yes 12 4 (33.3%) 8 (66.7%) 5 (41.7%) 7 (58.3%) 4 (33.3%) 8 (66.7%)
Perineural invasion
 No 54 24 (44.4%) 30 (55.6%) 0.535 31 (60.8%) 5 (39.2%) 0.917 34 (63.0%) 20 (37.0%) 0.293
 Yes 9 5 (55.6%) 4 (44.4%) 5 (55.6%) 4 (44.4%) 4 (44.4%) 5 (55.6%)

*, p < 0.05; **, p < 0.01.