CUR	Curcumin
TLR4	The toll-like receptor 4
EVs	extracellular vesicles
exocur	curcumin encapsulated or loaded exosomes
CUR-EXO	curcumin-primed exosomes
MESC-ExoCUR	curcumin-loaded embryonic stem cell exosomesEsosomes Curcumin
miRNA,	miRNAs, MicroRNAs
TLRs	Toll-like Receptors
PRRs	pattern-recognition receptors
PAMPs	pathogen-associated molecular patterns
TIR	Toll/IL-1 receptor; LRRs, leucine-rich repeats
NF-κB	nuclear factor-κB; LPS, lipopolysaccharide
LBP	LPS binding protein
MD-2	myeloid differentiation protein 2
MyD88	myeloid differentiation primary response protein 88
MAL	MyD88-adaptor-like
TIRAP	TIR domain-containing adaptor protein
TRIF	TIR domain-containing adaptor
TICAM-1	TIR domain-containing adaptor molecule-1
TRAM	TRIF-related adaptor molecule
AP-1	activating protein-1
IRAK	IL-1R-associated kinase
TNF	tumour necrosis factor
TRAF6	receptor-associated factor-6
MAP	mitogen-activated protein
IRAK-1	kinase Interleukin-1 receptor-associated kinase
TRAF6	TNF Receptor Associated Factor 6
IRF3	interferon regulatory factor-3
CNS	central nervous system
TLRs	toll-like receptors
TNF	tumor necrosis factor
IL	interleukin
IRF3	interferon regulatory factor 3
TREM2	Triggering Receptor Expressed on Myeloid cells 2
TBI	traumatic brain injury
RA	Rheumatoid Arthritis
SpA	Spondiloartritis
OA	osteoarthritis
CRP	C-reactive protein
DAMPs	damage-associated molecular patterns
MMP	matrix metalloproteinase
NO	nitric oxide
PGE2	prostaglandin E2
AGEs	advanced glycation end products
MSU	monosodium urate
RA	rheumatoid arthritis