Table 1.

Transcription factors (TFs) and epigenetic modifications regulating microRNAs (miRNA) transcription in immune cells.

Cell Type	TF or Epigenetic Modification	Regulated miRNA	Correlation	References
Transcription factor
Granulocyte	PU.1	miR-223	Positive	[34]
Hematopoietic stem cell		miR-23a	Positive	[36,37]
Dendritic cell Macrophage		miR-142-3p	Positive	[38] [39]
THP-1	NF-κB	miR-146a	Positive	[44]
THP-1		miR-155	Positive	[47,49]
Macrophage		miR-33, miR-33*	Positive	[50]
Dendritic cell		miR-22	Positive	[51]
Macrophage	Ets2	miR-155	Positive	[47]
Treg cell	Foxp3	miR-155	Positive	[52]
Tfh	Bcl-6	miR-17, miR-20a	Negative	[53]
CD8+ T cell	NFAT	miR-31	Positive	[54]
Epigenetic modification
Macrophage	DNA methylation	miR-495	Negative	[55]
Macrophage	Histone demethylation	miR-146a	Negative	[56]
CD4+ T cell	DNA methylation	miR-21	Negative	[57]
B cell	Histone acetylation	miR-155, miR-181b	Positive	[58]