Figure 3.

Learning and response activity in a simple light–dark discrimination task (DSTLDD). (A) Learning of the DSTLDD rule: accuracy increased across initial acquisition trials at 6 months and redeterminations, which occurred at 10 and 11 months of age; initial accuracy improved across trial days at 6 months and responses were more accurate at 10 months. Overall, rTg-DI responses were as accurate as WT. (B) DSTLDD average trials completed: rats responded as actively and therefore completed as many trials at 6 months; however, at 10 months rTg-DI responded less than WT and this pattern of diminished responding persisted at 11 months. # p < 0.05. Data represent mean + SEM.