Table 1.
Number of DEG in comparisons of each progestin vs. vehicle in the absence or presence of estradiol.
| Comparison | Up-Regulated DEG (FC ≥ 1.5) | Down-Regulated DEG (FC ≥ 1.5) | Total DEG | |
|---|---|---|---|---|
| Progestins without E2 | LNG vs. Vh | 249 | 304 | 553 |
| MPA vs. Vh | 122 | 129 | 251 | |
| NETA vs. Vh | 243 | 352 | 595 | |
| P4 vs. Vh | 55 | 61 | 116 | |
| E2 | E2 vs. Vh | 88 | 76 | 164 |
| Progestins + E2 | E2LNG vs. Vh | 233 | 338 | 571 |
| E2MPA vs. Vh | 259 | 350 | 609 | |
| E2NETA vs. Vh | 247 | 298 | 545 | |
| E2P4 vs. Vh | 208 | 314 | 522 |
E2: estradiol; MPA: medroxyprogesterone acetate; LNG: levonorgestrel; NETA: norethindrone acetate; FC: fold change; DEG: differentially expressed genes.