Figure 1.

Effects of Calebin A and/or 5-Fluorouracil (5-FU) on TNF-β-promoted cell proliferation in colorectal cancer cells (CRC) cells in the monolayer culture. Serum-starved cultures of HCT116 (A) and HCT116R (B) cell lines were treated as described in the Materials and Methods section. Cell viability and proliferation were evaluated with the MTT method. All assays were performed at least three times. p < 0.05 (*) and p < 0.01 (**) indicate a significant difference compared to the control group.