Figure 1.
(A) Inhibitory effect of DMSO extract of flesh and peel of raw Jabara, as well as the extract of fermented Jabara (four weeks) on β-hexosaminidase (β-hex) release from mast cells. IgE-sensitized mast cells (1.0 × 105 cells/well) were preincubated with each extract at 37 °C for 15 min prior to 30 min stimulation with DNP-HSA. Data represent one of at least three trials that showed similar results. Data are presented as mean (SD). **p < 0.01, two-tailed Student’s t-test. (B,C) Inhibitory effect of DMSO extract of fermented Jabara on cytokine production in mast cells. Mast cells were stimulated with 10 ng/mL DNP-HSA for 6 h with or without the addition of fermented Jabara. IL-6 (B) and IL-13 (C) production were measured by ELISA. Data represent one of at least three trials that showed similar results. Data are presented as mean (SD). *p < 0.05, two-tailed Student’s t-test.