| ECM | Extracellular matrix |
| OA | Osteoarthritis |
| ADAMTS | A disintegrin and metalloprotease with thrombospondin motifs |
| MMP | Matrix metallopeptidase |
| EO | Endochondral ossification |
| SOX9 | SRY-box 9 |
| COL2A1 | Collagen type II, alpha 1 |
| ACAN | Aggrecan |
| RUNX2 | Runt-related transcription factor 2 |
| SA-βgal | Senescence-associated beta-galactosidase |
| SASP | Senescence-associated secretory phenotype |
| ROS | Reactive oxygen specie |
| SIPS | Stress-induced premature senescence |
| TNF-α | Tumor necrosis factor-α |
| VEGF IHH |
Vascular endothelial growth factor Indian hedgehog |
| COL10A1 | Collagen type X, alpha 1 |
| ALK5 | Activin-like kinase 5 |
| DMM | Destabilization of the medial meniscus |
| PTHrP BMP |
Parathyroid hormone-related protein Bone morphogenetic protein |
| H2O2 GAG |
Hydrogen peroxide Glycosaminoglycan |
| NO JNK AGE ALP |
Nitric oxide c-Jun N-terminal kinases Advanced glycation end product Alkaline phosphatase |
| ACLT | Anterior cruciate ligament transection |
Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.