Table 1.

Structural data for human and mouse nucleotide-binding domain 1 (NBD1).

PDB Code	Organism	Resol. (Å)	Features	Complex with	Ref.
6GJS	H. sapiens	1.95	WT	ATP and 2 nanobodies	[22]
6GJU	H. sapiens	2.6	WT	nanobody
6GJQ	H. sapiens	2.49	WT	nanobody
6GK4	H. sapiens	2.91	WT	ATP and 2 nanobodies
6GKD	H. sapiens	2.99	WT	ATP and 2 nanobodies
4WZ6	H. sapiens	2.05	F508del, 3 stabilizing mutations	ATP	[23]
2PZE	H. sapiens	1.7	WT dimer	ATP	[24]
2PZF	H. sapiens	2.0	WT/F508del dimer	ATP
2PZG	H. sapiens	1.8	WT	ATP
2BBO	H. sapiens	2.55	F508del	ATP	[25]
2BBS	H. sapiens	2.05	WT, 3 stabilizing mutations	ATP
2BBT	H. sapiens	2.3	WT, 2 stabilizing mutations	ATP
1XMI	H. sapiens	2.25	WT	ATP	[26]
1XMJ	H. sapiens	2.3	F508del	ATP
5TF7	H. sapiens	1.93	WT	ATP	[27]
5TF8	H. sapiens	1.86	WT	dTTP
5TFA	H. sapiens	1.87	WT	dUTP
5TFB	H. sapiens	1.87	WT	7-methyl-GTP
5TFC	H. sapiens	1.92	WT	GTP
5TFD	H. sapiens	1.89	WT	CTP
5TFF	H. sapiens	1.89	WT	UTP
5TFG	H. sapiens	1.91	WT	5-methyl-UTP
5TFI	H. sapiens	1.89	WT	dGTP
5TFJ	H. sapiens	1.85	WT	dCTP
3SI7	Mouse	2.25	F508del	ATP	[28]
1XF9	Mouse	2.7	F508S	ATP	[7]
1XFA	Mouse	3.1	F508R	ATP
1Q3H	Mouse	2.5	F508R	ANP	[29]
1R10	Mouse	3.0	WT plus R-domain	ATP
1R0Z	Mouse	2.35	WT plus R-domain	ATP
1R0Y	Mouse	2.55	WT plus R-domain	ADP
1R0X	Mouse	2.2	WT plus R-domain	ATP
1R0W	Mouse	2.2	WT apo form	-

dTTP: thymidine-5′-triphosphate; dUTP: deoxyuridine-5′-triphosphate. H. sapiens: Homo sapiens