Ab	Antibody
ADAP	Adhesion and Degranulation Promoting Adapter Protein
AICD	Activation-induced cell death
APC	Antigen-presenting cell
Apo2L	Apo2 ligand (TRAIL)
BCR	B-cell receptor for antigen
CAR	Chimeric Antigen Receptors
cIS	Central region of the immune synapse
cSMAC	Central supramolecular activation cluster
DC	Dendritic cells
CTL	Cytotoxic T lymphocytes
DAG	Diacylglycerol
DGKα	Diacylglycerol kinase α
dSMAC	Distal supramolecular activation cluster
EM	Electron microscopy
ESCRT	Endosomal sorting complex required for traffic
EV	Extracellular vesicle
F-actin	Filamentous actin
Fact-low	F-actin-low region at the centre of the immune synapse
FasL	Fas ligand
FDC	Follicular Dendritic cells
ILV	Intraluminal vesicles
IS	Immune synapse
MHC	Major histocompatibility complex
miRNA	MicroRNA
MVB	Multivesicular bodies
MTOC	Microtubule-organizing center
NK	Natural killer cell
OVA	Ovalbumin
PBL	Peripheral blood lymphocytes
PKC	Protein kinase C
PKCδ	Protein kinase C δ isoform
PLC	Phospholipase C
pMHC	Peptide/MHC complex
pSMAC	Peripheral supramolecular activation cluster
SL	Secretory lysosomes
SLE	Systemic lupus erythematosus
SMAC	Supramolecular activation cluster
TCR	T-cell receptor for antigen
Th	T helper
TLR	Toll-like receptors
Treg	T regulatory cells