Table 1.

Clinicopathological Variables and circHMCU Expression in 267 Breast Cancer Patients

Variables	Classifier	Low circHMCU (n = 134)	High circHMCU (n = 133)	Total	p Value
Age	≤50	71	74	145	0.755
	>50	63	59	122
Menopause	no	73	64	137	0.359
	yes	61	69	130
Histologic grade	I	8	1	9
	II	93	84	177	0.013
	III	33	48	81
Lymph node metastasis	no	82	61	143	0.017
	yes	52	72	124
T stage	T1	78	49	127
	T2	53	79	132	0.002
	T3/T4	3	5	8
N stage	N0	82	61	140
	N1/N2	51	65	122	0.009
	N3	1	7	5
ER	negative	15	39	54	<0.001
	positive	119	94	213
PR	negative	24	42	66	0.014
	positive	110	91	201
HER2	negative	106	84	190	0.006
	positive	28	49	77
Molecular subtype	TNBC	10	21	31	0.053
	non-TNBC	124	112	236
Ki-67 scores	low	42	31	73	0.182
	high	92	102	194

T, tumor; N, node; ER, estrogen receptor; PR, progesterone receptor; HER2, human epidermal growth factor receptor-2.