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. 2020 Apr 5;21(7):2528. doi: 10.3390/ijms21072528
AF4 ALL1-fused gene from chromosome 4 protein
AF9 ALL1-fused gene from chromosome 9 protein
ALL Acute lymphoid leukemia
AML Acute myeloid leukemia
AP-1 Activator protein 1
Ara-C Cytarabine
Atf3 Activating transcription factor 3
AURK Aurora kinase
BCR-ABL Breakpoint cluster region - abelson 1
Btg2 B-cell translocation gene 2
CDK Cyclin-dependent kinase
dHSC Dormant hematopoietic stem cell
EGR-1 Early growth response protein 1
ER Estrogen receptor
ERK Extracellular signal-regulated kinase
ET Essential thrombocythaemia
FDA U.S. Food and Drug Administration
FLT3 FMS-like tyrosine kinase 3
HCK Hemopoietic cell kinase
HER2 Human epidermal growth factor receptor 2
HSC Hematopoietic stem cell
HSPC Hematopoietic stem/progenitor cell
IL Interleukin
ITD Internal tandem duplications
JAK2 Janus kinase 2
Klf6 Krueppel-like factor 6
KMT2A Lysine-specific MethylTransferase 2A
LSC Leukemic stem cell
LSK Purified Lineage Sca1+cKit+ cell
MDS Myelodysplastic syndrome
MLL Mixed-lineage leukemia
MLLr MLL-rearranged
MPN Myeloproliferative neoplasm
MTG8 Myeloid translocation gene on 8
NF-κB Nuclear factor kappa-light-chain-enhancer of activated B cells
NFY Nuclear transcription factor Y
NFκBiz NF-κB inhibitor zeta
OS Overall survival
PDGFR Platelet-derived growth factor receptor
PIM1 Proviral integration site for Moloney murine leukemia virus 1
Pmaip1 Phorbol-12-myristate-13-acetate-induced protein 1
PMF Primary myelofibrosis
Poly (I:C) Polyinosinic:polycytidylic acid
Protein kinase B PKB
PV Polycythaemia vera
R/R Refractory/recurrent
RAS Rat sarcoma
RB Retinoblastoma
RNA-Seq RNA sequencing
RUNX1 Runt-related transcription factor 1
shRNA Small hairpin RNA
Socs3 Suppressor of cytokine signaling 3
SP1 Specific protein 1
SRC v-Src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog
STAT Signal transducer and activator of transcription
TKD Tyrosine kinase domain
TKI Tyrosine kinase inhibitor
VEGF-A Vascular endothelial growth factor A