AF4 |
ALL1-fused gene from chromosome 4 protein |
AF9 |
ALL1-fused gene from chromosome 9 protein |
ALL |
Acute lymphoid leukemia |
AML |
Acute myeloid leukemia |
AP-1 |
Activator protein 1 |
Ara-C |
Cytarabine |
Atf3 |
Activating transcription factor 3 |
AURK |
Aurora kinase |
BCR-ABL |
Breakpoint cluster region - abelson 1 |
Btg2 |
B-cell translocation gene 2 |
CDK |
Cyclin-dependent kinase |
dHSC |
Dormant hematopoietic stem cell |
EGR-1 |
Early growth response protein 1 |
ER |
Estrogen receptor |
ERK |
Extracellular signal-regulated kinase |
ET |
Essential thrombocythaemia |
FDA |
U.S. Food and Drug Administration |
FLT3 |
FMS-like tyrosine kinase 3 |
HCK |
Hemopoietic cell kinase |
HER2 |
Human epidermal growth factor receptor 2 |
HSC |
Hematopoietic stem cell |
HSPC |
Hematopoietic stem/progenitor cell |
IL |
Interleukin |
ITD |
Internal tandem duplications |
JAK2 |
Janus kinase 2 |
Klf6 |
Krueppel-like factor 6 |
KMT2A |
Lysine-specific MethylTransferase 2A |
LSC |
Leukemic stem cell |
LSK |
Purified Lineage− Sca1+cKit+ cell |
MDS |
Myelodysplastic syndrome |
MLL |
Mixed-lineage leukemia |
MLLr |
MLL-rearranged |
MPN |
Myeloproliferative neoplasm |
MTG8 |
Myeloid translocation gene on 8 |
NF-κB |
Nuclear factor kappa-light-chain-enhancer of activated B cells |
NFY |
Nuclear transcription factor Y |
NFκBiz |
NF-κB inhibitor zeta |
OS |
Overall survival |
PDGFR |
Platelet-derived growth factor receptor |
PIM1 |
Proviral integration site for Moloney murine leukemia virus 1 |
Pmaip1 |
Phorbol-12-myristate-13-acetate-induced protein 1 |
PMF |
Primary myelofibrosis |
Poly (I:C) |
Polyinosinic:polycytidylic acid |
Protein kinase B |
PKB |
PV |
Polycythaemia vera |
R/R |
Refractory/recurrent |
RAS |
Rat sarcoma |
RB |
Retinoblastoma |
RNA-Seq |
RNA sequencing |
RUNX1 |
Runt-related transcription factor 1 |
shRNA |
Small hairpin RNA |
Socs3 |
Suppressor of cytokine signaling 3 |
SP1 |
Specific protein 1 |
SRC |
v-Src sarcoma (Schmidt-Ruppin A-2) viral oncogene homolog |
STAT |
Signal transducer and activator of transcription |
TKD |
Tyrosine kinase domain |
TKI |
Tyrosine kinase inhibitor |
VEGF-A |
Vascular endothelial growth factor A |