Table 1.
The chemical structures of the potential inhibitors of SIRT6 selected from Traditional Chinese Medicines (TCMS) using AutoDock methods.
Compound | English Name | Chinese Herb Medicine | Structure Formula | Binding Energy (kcal/mol) |
---|---|---|---|---|
1 | Puerarin | Ge Geng |
![]() |
−7.05 |
2 | Shikonofuran E | Zi Cao |
![]() |
−6.1 |
3 | Daidzin | Ge Geng |
![]() |
−7.93 |
4 | Sophoricoside | Huai Hua |
![]() |
−6.73 |
5 | Baohuoside I | Epimedium koreanum Nakai |
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−6.71 |
6 | Carthamin | Hong Hua |
![]() |
−6.14 |
7 | Liquiritin | Cu Mao; Gan Cao |
![]() |
−7.74 |
8 | Wogonoside | Huang Qin; Chuan Huang Qin; Dian Huang Qin |
![]() |
−6.92 |
9 | BAS13555470 (Compound 9) |
- |
![]() |
−8.66 |
10 | Scutellarin | Ban Zhi Lian; Huang Qin |
![]() |
−9.43 |