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. 2020 Apr 5;21(7):2533. doi: 10.3390/ijms21072533

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© 2020 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Metabolism of lipidoses (a) Impact of lipid trafficking in Niemann-Pick type C disease. (b) Impact of lipid metabolism in other lysosomal storage disorders. Abbreviations: ACAT, Cholesterol acyltransferase; CE, Cholesterol Ester; FC, Free Cholesterol; Hex, Hexadecanal; PE, Phosphatidylethanolamine; S1P, Sphingosine-1-Phosphate; Sph, Sphingosine; SphK1, Sphingosine Kinase; Sphingosine-1-Phosphate-Lyase; GlcCer, Glucosylceramide; NeuAc; N-acetyl nueraminc acid, GalCer, Galactosylceramide; Gal-GlcCer, Lactosylceramide; GalNAcβ3GalαGalβ4GlcCer, Globoside; GalαGalβ4GlcCer, Isoglobotriosylceramide.

Metabolism of lipidoses (a) Impact of lipid trafficking in Niemann-Pick type C disease. (b) Impact of lipid metabolism in other lysosomal storage disorders. Abbreviations: ACAT, Cholesterol acyltransferase; CE, Cholesterol Ester; FC, Free Cholesterol; Hex, Hexadecanal; PE, Phosphatidylethanolamine; S1P, Sphingosine-1-Phosphate; Sph, Sphingosine; SphK1, Sphingosine Kinase; Sphingosine-1-Phosphate-Lyase; GlcCer, Glucosylceramide; NeuAc; N-acetyl nueraminc acid, GalCer, Galactosylceramide; Gal-GlcCer, Lactosylceramide; GalNAcβ3GalαGalβ4GlcCer, Globoside; GalαGalβ4GlcCer, Isoglobotriosylceramide.