ADP	adenosine diphosphate
AMPKa	AMP-activated protein kinase a
APC	antigen presenting cell
ATP	adenosine triphosphate
ATRA	all-trans retinoic acid
CAF	cancer-associated fibroblasts
COX-2	cyclooxygenase-2
CT	computer tomography
CTLA-4	cytotoxic T lymphocyte-associated protein-4
CXCL	C-X-C motif chemokine ligand
CXCR	C-X-C motif chemokine receptor
DCR	disease control rate
EV	extracellular vesicles
FAP	fibroblast activation protein
FGF-2	fibroblast growth factor 2
FOXP3+	forkhead box protein P3
G-CSF	granulocyte-colony stimulating factor
GM-CSF	granulocyte-macrophage colony stimulating factor
HIF-1α	hypoxia-inducible factor-1α
ICI	immune checkpoint inhibitors
IFN	interferon
IL	interleukin
LAG-3	lymphocyte activation gene-3
LSECtin	liver sinusoidal endothelial cell lectin
MDSC	myeloid-derived suppressor cells
MHC	major histocompatibility complex
MMP-9	matrix metallopeptidase 9
MRI	magnetic resonance imaging
NK	natural killer
NO	nitric oxide
ORR	objective response rate
OS	overall survival
PD-1	programmed cell death protein 1
PDE	phosphodiesterase
PD-L1	programmed cell death ligand 1
PD-L2	programmed cell death ligand 2
PFS	progression free survival
PMN	polymorphonuclear
ROS	reactive oxygen species
RT	radiation therapy
SD	stable disease
TAM	tumor-associated macrophages
TAN	Tumor-associated neutrophils
TCR	T-cell receptor
TGF-β	transforming growth factor-β
TIGIT	T cell immunoreceptor with Ig and ITIM domains
TIM-3	T-cell immunoglobulin- and mucin domain- containing molecule 3
TME	tumor microenvironment
Treg	regulatory T cells
T-VEC	talimogen laherparepvec alimogen laherparepvec
VEGF	vascular endothelial growth factor