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. 2020 Apr 21;40(4):BSR20194448. doi: 10.1042/BSR20194448

Table 1. Comparison of clinical characteristics between POCD group and non-POCD group at 21 days after operation.

Parameters POCD group (n=98) Non-POCD group (n=264) t/χ2 P
Demographics
Age, year 68.2 ± 5.6 66.7 ± 6.2 2.098 0.037
Male, n (%) 58 (59.1%) 147 (55.7%) 0.357 0.550
BMI, kg/m2 23.1 ± 9.3 22.6 ± 8.7 0.477 0.634
Education, y 6.5 ± 2.8 7.3 ± 2.6 1.910 0.057
Smoking, n (%) 43 (43.9%) 110 (41.7%) 0.143 0.705
Drinking, n (%) 34 (34.7%) 87 (33.0%) 0.097 0.755
Physical activity 1.762 0.414
<1 time/week 48 (49.0%) 117 (44.3%)
1–3 times/week 22 (22.4%) 52 (19.7%)
>3 times/week 28 (28.6%) 95 (36.0%)
Hypertension, n (%) 90 (91.8%) 227 (86.0%) 2.248 0.134
Diabetes, n (%) 43 (43.9%) 85 (32.2%) 4.266 0.039
Hyperlipidemia, n (%) 55 (56.1%) 144 (54.5%) 0.072 0.789
Chronic renal dysfunction, n (%) 8 (8.2%) 90 (7.6%) 0.035 0.853
Aortic plaque, n (%) 50 (51.0%) 89 (33.7%) 9.052 0.003
Carotid artery stenosis, n (%) 40 (40.8%) 74 (28.0%) 5.416 0.020
Cerebrovascular disease, n (%) 34 (34.7%) 37 (14.0%) 19.384 <0.001
Blood biochemical parameters
Triglyceride, mmol/dl 1.7 ± 1.1 1.5 ± 0.9 1.765 0.078
HDL-C, mmol/dl 1.1 ± 0.3 1.2 ± 0.3 2.818 0.005
LDL-C, mmol/dl 3.2 ± 1.0 3.3 ± 0.9 0.911 0.363
Total cholesterol, mmol/dl 5.4 ± 0.9 5.2± 0.9 1.879 0.061
Fasting plasma glucose, mmol/l 6.7 ± 2.2 5.6 ± 1.2 6.058 <0.001
Hs-CRP, ng/l 9.0 ± 14.3 5.2± 11.2 2.634 0.009
Red blood cell, ×1012/l 4.5 ± 0.6 4.4 ± 0.5 3.197 0.111
White blood cell, ×109/l 6.5 ± 2.4 5.8 ± 2.5 2.393 0.017
Red cell distribution width (%) 17.4 ± 0.2 13.2 ± 0.4 11.814 <0.001
Blood platelet, ×109/l 210.6 ± 64 205.4 ± 54 0.773 0.440
Hemoglobin, g/l 132.5 ± 13.4 135.6 ± 14.8 1.815 0.070
Perioperative parameters
Duration of surgery, h 4.3 ± 1.2 3.8 ± 0.9 4.270 <0.001
Surgery methods 0.187 0.665
Off-pump 38 (38.8%) 109 (41.3%)
On-pump 60 (61.2%) 155 (58.7%)
Baseline VAS 4.4 ± 0.9 4.3 ± 1.0 0.868 0.386
Baseline MMSE 25.7 ± 2.6 26.2 ± 2.3 1.773 0.077
Baseline SAS 24.6 ± 2.5 24.1 ± 2.3 1.794 0.074
Baseline SDS 24.4 ± 3.3 25.0 ± 2.8 1.723 0.086